翻訳と辞書 Words near each other ・ Serve Jah ・ Serve the Ego ・ Serve the People ・ Serve the People (Norway) ・ ServedBy The Net ・ Serveis Ferroviaris de Mallorca ・ Servemehere ・ Serukalathur Sama ・ Serukeirewa ・ Serule ・ Serum ・ Serum (blood) ・ Serum albumin ・ Serum amyloid A ・ Serum amyloid A1 ・ Serum amyloid P component ・ Serum chloride ・ Serum free light-chain measurement ・ Serum Institute of India ・ Serum iron ・ Serum Metabolome Database ・ Serum protein electrophoresis ・ Serum response factor ・ Serum sickness ・ Serum sickness-like reaction ・ Serum total protein ・ Serum-ascites albumin gradient ・ Serum-derived bovine immunoglobulin/protein isolate ・ Serum-separating tube ・ Serumakkanallur Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Serum amyloid P component ： ウィキペディア英語版 Serum amyloid P component The serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=325 )〕 ==In amyloidosis== AP makes up 14% of the dry mass of amyloid deposits and is thought to be an important contributor to the pathogenesis of a related group of diseases called the Amyloidoses. These conditions are characterised by the ordered aggregation of normal globular proteins and peptides into insoluble fibres which disrupt tissue architecture and are associated with cell death. AP is thought to decorate and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal via the normal protein scavenging mechanisms. This association is utilised in the routine clinical diagnostic technique of SAP scintigraphy whereby radio-labelled protein is injected into patients to locate areas of amyloid deposition. The SAP-amyloid association has also been identified as a possible drug target for anti-amyloid therapy, with the recent development and first stage clinical trials of a compound called CPHPC (R-1- pyrrolidine-2-carboxylic acid), a small molecule able to strip AP from deposits by reducing levels of circulating SAP. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Serum amyloid P component」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.